They don't mess about in Denver, Colorado. This billboard is definitely in your face as it forms part of a national ad campaign by the Freedom from Religion Foundation. Read the story here; see the FfRF here.
The Foundation is the USA’s largest association of agnostics, atheists and devout secularists, and has been active in Denver courts for many years. Robert Tiernan, who's a Denver lawyer, and the Foundation once worked to halt city sponsorship of a day of prayer promoted by the mayor’s office.
The billboard, in Fox Street, just six blocks from the state Capitol, is costing about $3,000.